E. G. Daily

Tommy Pickles (voice)

Nancy Cartwright

Chuckie Finster (voice)

Kath Soucie

Phil DeVille / Lil DeVille / Betty DeVille (voice)

Dionne Quan

Kimi Watanabe-Finster (voice)

Tim Curry

Nigel Thornberry (voice)

Joe Alaskey

Lou Pickles (voice)

Tress MacNeille

Charlotte Pickles (voice)

Michael Bell

Drew Pickles / Charles 'Chaz' Finster, Sr. (voice)

Julia Kato

Kira Watanabe-Finster (voice)

Phil Proctor

Howard DeVille (voice)

Jack Riley

Stuart 'Stu' Pickles (voice)

Tara Strong

Dil Pickles (voice)