Robert Downey Jr.

Sherlock Holmes

Jude Law

Dr. John Watson

Rachel McAdams

Irene Adler

Mark Strong

Lord Henry Blackwood

Eddie Marsan

Inspector Lestrade

Robert Maillet

Dredger

Geraldine James

Mrs. Hudson

Kelly Reilly

Mary Morstan

William Houston

Constable Clark

Hans Matheson

Lord Coward

James Fox

Sir Thomas Rotheram

William Hope

Ambassador Standish